From a theoretical view, the mode is related to a particular chord type/function of the chord. You can play anything you like over a chord, but then it becomes something else.
Modal pentatonics can be useful - try a B minor pentatonic over a Cmajor7 chord in the key of G - instant Lydian sound. It is only one approach, and so it cna be good for variation, but like anything can get old pretty quickly.
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