Blue Jean Blues (ZZ Top original artist?) illustrates that point well. The song is a 12 bar blues in the key of Bm. Solo is easily accomplished with Bm pentatonic, or B blues... but YOU MUST make the chord changes with the rhythm section. Never leaving the "Scale" but always playing those "chords" in that scale.
When they goto the Em, you must hit it... when they change back to Bm... you must acknowledge that in your solo. Then the last change to F# is perhaps the most crucial as it sets up the climax of the solo and the turn around.
All of the licks between the verses also are just glorified runs to the coming chord change, whatever you play you MUST end with a salutation to the chord change.
So its not a "Scales vs Chord tones" debate in my opinion... but more of "Chords are what you do with Scales" revelation. What is fingerpicking if not "glorified soloing" over chord structure. "Finding" the melody of the song in the chords.
Yes, you must do more than simply Arpeggiate the chords over and over...
Which I would like to add as a side note I stumbled upon weeks before finding this forum... 26 years into being a organic guitar tuning device/Riff junkie I have an epiphiny... and then find this fantastic site where its all laid out in a straightforward and insightful fashion.

Remember, wherever you go... there you are.